Description

Dihydroouabain is a potent cardiac glycoside derivative, specifically a reduced form of ouabain. This compound is of significant interest in biochemical and pharmacological research due to its role as a specific inhibitor of the sodium-potassium ATPase (Na+/K+-ATPase) pump. It is primarily utilized by researchers and manufacturers in the life sciences sector for studying ion transport mechanisms, cellular signaling pathways, and for the development of cardiovascular therapeutics.

Application

• Biochemical Research: As a high-affinity, selective inhibitor of Na+/K+-ATPase for investigating ion transport and enzyme kinetics in vitro.
• Pharmacological Studies: Used in cardiac research models to study inotropic effects, cellular calcium handling, and heart failure mechanisms.
• Neurobiological Research: Applied in studies of neuronal excitability, neurotransmitter release, and the role of ion pumps in neurological disorders.
• Reference Standard: Serves as a critical analytical standard in pharmaceutical quality control and method development for related cardiac glycosides.
• Drug Discovery & Development: A key tool compound for screening and validating new therapeutic agents targeting the ATPase pump.
• Academic & Institutional Labs: Fundamental reagent for graduate and post-doctoral research in physiology, pharmacology, and cell biology.

Basic Information

Product Name	Dihydroouabain
CAS No.	1183-35-3
Molecular Formula	C29H46O12
Molecular Weight	586.67 g/mol
Synonyms	Dihydroouabain; 3β,5,11α,14,19-Pentahydroxy-5β-card-20(22)-enolide; Strophanthidin 3β-L-rhamnoside, dihydro-; Ouabain, dihydro-; G-Strophanthidin rhamnoside, dihydro-; NSC 19083; DHO
EINECS	214-648-8

Quality Control

Our Dihydroouabain is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical experiments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.