Description

Neodiosgenin(3Beta,25S) Acetate is a high-purity, semi-synthetic steroidal sapogenin derivative, serving as a critical intermediate in advanced pharmaceutical synthesis. Its value lies in providing a defined stereochemical starting point for the production of complex steroid-based active pharmaceutical ingredients (APIs). This compound is essential for research and manufacturing organizations in the pharmaceutical, biotechnology, and fine chemical sectors, particularly those focused on developing novel steroidal drugs and hormone therapies.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of steroidal drugs, including corticosteroids, sex hormones, and cardiac glycosides.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new therapeutic agents targeting hormone receptors.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Process Chemistry: Employed in the scalable, multi-step synthesis of complex steroid molecules requiring the (25S) configuration.
• Biochemical Research: Utilized in studies investigating enzyme inhibition, metabolic pathways, and steroidal biosynthesis.

Basic Information

Product Name	Neodiosgenin(3Beta,25S) Acetate
CAS No.	1180-12-7
Molecular Formula	C29H44O4
Molecular Weight	456.66 g/mol
Synonyms	Neodiosgenin Acetate; (25S)-Spirost-5-en-3β-ol, 3-acetate; 3β-Hydroxy-5-spirosten-11-one 3-acetate; Diosgenin acetate isomer; (3β,25S)-3-(Acetyloxy)spirost-5-en; 25S-Neodiosgenin Acetate; 25-Epineodiosgenin Acetate
EINECS	Contact for details

Quality Control

Our Neodiosgenin(3Beta,25S) Acetate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the stringent requirements for pharmaceutical intermediates. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (25S isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.