Description

3Beta,21-Dihydroxy-16Alpha-Methylpregn-5-En-20-One 21-Acetate is a high-purity steroid intermediate of significant commercial and research importance. This compound serves as a critical building block in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of corticosteroids and other therapeutic agents. Its defined structure and purity are essential for ensuring the efficacy and safety of downstream pharmaceutical products.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the manufacture of corticosteroid drugs, including anti-inflammatory and immunosuppressive agents.
• Research & Development: Used in academic and industrial laboratories for studying steroid metabolism, receptor binding, and the synthesis of novel steroid analogues.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce specific steroidal frameworks into target molecules.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical production.
• Process Development: Utilized in scaling up and optimizing synthetic routes for steroid-based APIs under cGMP conditions.

Basic Information

Product Name	3Beta,21-Dihydroxy-16Alpha-Methylpregn-5-En-20-One 21-Acetate
CAS No.	1173-09-7
Molecular Formula	C24H36O5
Molecular Weight	404.54 g/mol
Synonyms	16α-Methylpregnenolone 21-Acetate; 21-Acetoxy-16α-methylpregnenolone; 3β,21-Dihydroxy-16α-methylpregn-5-en-20-one 21-acetate; 16α-Methyl-21-acetoxypregnenolone; (3β)-3,21-Dihydroxy-16α-methylpregn-5-en-20-one 21-acetate; 16α-Methyl-δ5-pregnenolone 21-acetate; 21-Acetoxy-3β-hydroxy-16α-methylpregn-5-en-20-one
EINECS	Contact for details

Quality Control

Our 3Beta,21-Dihydroxy-16Alpha-Methylpregn-5-En-20-One 21-Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the stringent requirements for pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled and stored away from direct light exposure to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.