Description

8-Azaguanosine-5'-Monophosphate is a chemically modified nucleotide analog, serving as a crucial biochemical tool and research intermediate. Its structural similarity to natural guanosine nucleotides makes it valuable for studying enzyme mechanisms, nucleic acid metabolism, and as a potential precursor for novel therapeutic agents. This compound is primarily utilized by researchers and developers in the fields of pharmaceutical development, biochemical research, and molecular biology.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for nucleoside kinases, phosphatases, and polymerases.
• Pharmaceutical Intermediates: Acts as a key building block in the synthesis of novel antiviral or anticancer nucleoside analogs.
• Metabolic Pathway Studies: Employed to investigate purine salvage pathways and nucleotide metabolism in cellular systems.
• Molecular Probe Development: Serves as a starting material for creating labeled probes to study nucleic acid interactions and functions.
• Enzyme Mechanism Elucidation: Useful for probing the active sites and catalytic mechanisms of nucleotide-binding enzymes due to its modified base.

Basic Information

Product Name	8-Azaguanosine-5'-Monophosphate
CAS No.	1165-66-8
Molecular Formula	C10H14N6O8P
Molecular Weight	377.23 g/mol
Synonyms	8-Aza-GMP; 8-Azaguanosine monophosphate; 8-Aza-5'-GMP; Guanine-8-aza-riboside 5'-monophosphate; 8-Azaguanosine 5'-(dihydrogen phosphate); 5'-Monophosphoric acid 8-azaguanosine ester; 8-Aza-5'-guanylic acid
EINECS	Contact for details

Quality Control

Our 8-Azaguanosine-5'-Monophosphate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.