Description

21-Hydroxypregnenolone is a key steroid intermediate and a biosynthetic precursor in the production of various corticosteroids and other steroid hormones. This compound is of significant importance for pharmaceutical research and development, particularly in the synthesis of complex therapeutic agents. It is primarily utilized by manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for the development of active pharmaceutical ingredients (APIs) and reference standards.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of corticosteroids like hydrocortisone and other adrenal hormones.
• Biochemical Research: Used as a reference standard and precursor in studies of steroidogenesis, enzyme activity, and metabolic pathways.
• API Development: Serves as a starting material or intermediate in the development of novel therapeutic steroid compounds.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized steroid derivatives.
• Diagnostic Reagents: Can be used in the formulation of calibrators and controls for diagnostic assays measuring steroid hormone levels.

Basic Information

Item	Detail
Product Name	21-Hydroxypregnenolone
CAS No.	1164-98-3
Molecular Formula	C21H32O3
Molecular Weight	332.48 g/mol
Synonyms	3β,21-Dihydroxypregn-5-en-20-one; Pregnenolone, 21-hydroxy-; 21-Hydroxy-5-pregnen-3β-ol-20-one; 21-Hydroxypregn-5-ene-3β,21-diol-20-one; 3β,21-Dihydroxy-5-pregnen-20-one; 21-Hydroxypregnenolone; δ5-Pregnen-3β,21-diol-20-one
EINECS	Contact for details

Quality Control

Our 21-Hydroxypregnenolone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical intermediates and research chemicals. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.