Description

11-β-Hydroxypregnenolone is a key steroid intermediate, specifically a hydroxylated derivative of pregnenolone. This compound is of significant value in the synthesis of more complex steroid hormones and active pharmaceutical ingredients (APIs). It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and contract research organizations (CROs) engaged in steroid chemistry and drug development.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of corticosteroids and other therapeutic steroid molecules.
• Biochemical Research: Used as a reference standard or substrate in enzymatic studies related to steroidogenesis and metabolic pathways.
• Hormone Analog Development: Serves as a starting material for the research and development of novel hormone analogs with potential therapeutic applications.
• Fine Chemical Synthesis: Employed in custom synthesis projects for producing high-value, specialized steroid compounds.
• Academic Research: Utilized in university and institutional labs for studies in organic chemistry, medicinal chemistry, and endocrinology.

Basic Information

Item	Detail
Product Name	11-β-Hydroxypregnenolone
CAS No.	1164-86-9
Molecular Formula	C21H32O3
Molecular Weight	332.48 g/mol
Synonyms	11β-Hydroxypregnenolone; 3β-Hydroxy-5-pregnen-11β-ol-20-one; 11β-Hydroxy-5-pregnen-3β-ol-20-one; 11β-Hydroxypregn-5-en-3β-ol-20-one; 11β-OH-Pregnenolone; 11β-Hydroxypregnenolone; 11β-Hydroxy-δ5-pregnenolone
EINECS	Contact for details

Quality Control

Our 11-β-Hydroxypregnenolone is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its light-sensitive and easily oxidized nature, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.