Description

4-Chloropregn-4-Ene-3,20-Dione is a key synthetic steroid intermediate, specifically a chlorinated pregnane derivative. This compound is valued for its role as a versatile building block in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of corticosteroids, progestogens, and other specialized steroid molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of various corticosteroid and progestogen APIs.
• Steroid Research & Development: Used as a standard or starting material in medicinal chemistry for developing novel steroid-based therapeutics.
• Fine Chemical Synthesis: Serves as a building block for creating custom steroid derivatives and analogs in contract manufacturing.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	4-Chloropregn-4-Ene-3,20-Dione
CAS No.	1164-81-4
Molecular Formula	C21H29ClO2
Molecular Weight	348.91 g/mol
Synonyms	4-Chloropregn-4-ene-3,20-dione; 4-Chloropregna-4-ene-3,20-dione; 4-Chloro-4-pregnene-3,20-dione; 4-Chloro-17α-pregn-4-ene-3,20-dione; 4-Chloro-17α-pregna-4-ene-3,20-dione; 4-Chloro-17α-pregn-4-en-3,20-dione; 4-Chloro-17α-pregna-4-en-3,20-dione; 4-Chloro-17α-pregn-4-en-3,20-dione
EINECS	Contact for details

Quality Control

Our 4-Chloropregn-4-Ene-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.