Description

16-Dehydropregnenolone is a key steroid intermediate with significant importance in the synthesis of complex pharmaceutical compounds. Its unique structure, featuring a conjugated dienone system, makes it a versatile building block for the production of various corticosteroids, progestins, and other bioactive steroids. This high-purity intermediate is essential for manufacturers in the pharmaceutical, research, and fine chemical sectors requiring reliable and consistent raw materials for advanced synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of corticosteroids like prednisolone and dexamethasone.
• Hormone Synthesis: Used in the production of progestogens and other steroidal hormones.
• Research & Development: Serves as a standard or starting material in medicinal chemistry research for developing new steroidal drugs.
• Fine Chemical Production: Employed in custom synthesis and the manufacture of specialized steroidal compounds for various applications.
• Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	16-Dehydropregnenolone
CAS No.	1162-53-4
Molecular Formula	C21H28O2
Molecular Weight	312.45 g/mol
Synonyms	16-Dehydroprogesterone; 16-Dehydropregnenolone; Pregna-5,16-dien-3β-ol-20-one; 3β-Hydroxypregna-5,16-dien-20-one; 16-DHP; NSC 32977; 5,16-Pregnadien-3β-ol-20-one
EINECS	214-574-6

Quality Control

Our 16-Dehydropregnenolone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR for identification, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.