Description

5-Iodocytidine is a halogenated nucleoside derivative, a crucial building block in organic synthesis and biochemical research. This modified cytidine is valued for its role in the development of oligonucleotide probes and as a key intermediate in pharmaceutical research, particularly for antiviral and anticancer agents. It serves the needs of research institutions, diagnostic developers, and pharmaceutical companies engaged in nucleoside chemistry and drug discovery.

Application

• Oligonucleotide Synthesis: Used as a modified monomer for incorporating iodine labels into DNA and RNA strands for probing and diagnostic applications.
• Pharmaceutical Intermediates: Serves as a critical precursor in the synthesis of novel nucleoside-based antiviral and anticancer therapeutics.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies to investigate nucleic acid metabolism and related pathways.
• Radiolabeling Precursor: Acts as a starting material for the synthesis of radioiodinated compounds used in medical imaging and tracer studies.
• Cross-linking Studies: Utilized in photochemical cross-linking experiments to study nucleic acid-protein interactions.

Basic Information

Product Name	5-Iodocytidine
CAS No.	1147-23-5
Molecular Formula	C9H12IN3O5
Molecular Weight	369.11 g/mol
Synonyms	5-Iodo-1-β-D-ribofuranosylcytosine; 5-Iodocytosine riboside; Cytidine, 5-iodo-; 1-(β-D-Ribofuranosyl)-5-iodocytosine; 5-I-Cyd; 5-I-Cytidine; 5-Iodo-1-(β-D-ribofuranosyl)cytosine; 5-Iodocytidine, 98+%
EINECS	214-549-6

Quality Control

Our 5-Iodocytidine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled and stored away from direct light exposure to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.