Description

1-Methylcytosin is a modified nucleobase derivative of cytosine, where a methyl group is substituted at the N1 position. This modification is crucial for research in nucleic acid chemistry, epigenetics, and the development of novel therapeutic agents. It serves as a key building block and reference standard for scientists and manufacturers in the pharmaceutical, biotechnology, and life science research sectors.

Application

• Pharmaceutical Intermediate: Used in the synthesis of nucleoside analogs and other active pharmaceutical ingredients (APIs) with potential antiviral or anticancer properties.
• Biochemical Research: Acts as a critical reagent in epigenetic studies, particularly in investigating DNA methylation patterns and their biological implications.
• Nucleic Acid Chemistry: Serves as a modified base for constructing oligonucleotides with specific properties for diagnostic probes or therapeutic oligonucleotides.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.
• Academic & Industrial R&D: Fundamental material for exploring new chemical entities in medicinal chemistry and developing novel biomaterials.

Basic Information

Product Name	1-Methylcytosin
CAS No.	1122-47-0
Molecular Formula	C5H7N3O
Molecular Weight	125.13 g/mol
Synonyms	1-Methylcytosine; N1-Methylcytosine; 1-Methyl-4-amino-2(1H)-pyrimidinone; 4-Amino-1-methyl-2(1H)-pyrimidinone; 2-Hydroxy-1-methyl-4-aminopyrimidine; 1-Methyl-4-aminouracil; Cytosine, 1-methyl-
EINECS	214-352-8

Quality Control

Our 1-Methylcytosin is manufactured under a quality management system. Each batch undergoes comprehensive analytical testing, including identity confirmation by IR spectroscopy and purity determination by HPLC, to ensure it meets stringent specifications for research and production use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.