Description

3-Chloropyridazine is a versatile halogenated heterocyclic building block with significant synthetic utility. Its core value lies in its reactivity, where the chlorine atom serves as a key site for nucleophilic substitution and cross-coupling reactions, enabling the construction of complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds with pyridazine-based scaffolds.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and insecticides, where the pyridazine ring contributes to biological activity.
• Material Science Research: Serves as a precursor for the development of ligands, organic semiconductors, and functional polymers.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Stille, and Buchwald-Hartwig amination reactions to form carbon-carbon and carbon-heteroatom bonds.
• Nucleophilic Substitution: The chlorine atom can be readily displaced by various nucleophiles (amines, alkoxides, thiols) to create diverse derivative libraries.
• Chemical Research & Development: A fundamental building block in medicinal chemistry and process chemistry for exploring new synthetic pathways.

Basic Information

Product Name	3-Chloropyridazine
CAS No.	1120-95-2
Molecular Formula	C4H3ClN2
Molecular Weight	114.53 g/mol
Synonyms	3-Chloro-1,2-diazine; 3-Chloropyridazine; Pyridazine, 3-chloro-; 1,2-Diazine, 3-chloro-; 3-Chloro-1,2-diazabenzene; 3-Chloropyridazine (technical grade); 3-CPZ; 3-Cl-Pyridazine
EINECS	214-316-4

Quality Control

Our 3-Chloropyridazine is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results for purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.