Description

Cinobufotalin is a bioactive steroidal cardiotonic compound, a key active ingredient derived from traditional sources. This high-purity compound is essential for research and development in the pharmaceutical and life sciences sectors, where precise molecular structure and consistent quality are paramount. It is primarily utilized by researchers and manufacturers focused on oncology, cardiology, and novel therapeutic agent development.

Application

• Pharmaceutical R&D: Serves as a critical reference standard and active pharmaceutical ingredient (API) in the development of anticancer and cardiotonic drugs.
• Biological Research: Used in biochemical and pharmacological studies to investigate mechanisms of action, cytotoxicity, and cell signaling pathways.
• Analytical Chemistry: Employed as a certified reference material (CRM) for method development, validation, and quality control in HPLC and LC-MS analysis.
• Preclinical Studies: A vital component in in vitro and in vivo studies for evaluating efficacy, pharmacokinetics, and safety profiles of new drug candidates.
• Natural Product Standardization: Used to standardize and authenticate extracts and formulations in the nutraceutical and traditional medicine sectors.

Basic Information

Product Name	Cinobufotalin
CAS No.	1108-68-5
Molecular Formula	C₂₆H₃₄O₇
Molecular Weight	458.55 g/mol
Synonyms	Bufotalin; Cinobufotaline; 3β,14β-Dihydroxy-5β-bufa-20,22-dienolide; Arenobufagin; Bufogenin B; Venobufagin; NSC-83265
EINECS	214-173-2

Quality Control

Our Cinobufotalin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and stringent tests for residual solvents and heavy metals. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity, the product should be stored under an inert atmosphere to prevent oxidation. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.