Description

Methyl 5-Chloro-1H-Indazole-3-Carboxylate is a high-purity organic building block and pharmaceutical intermediate of significant commercial importance. Its core value lies in its functionalized indazole scaffold, which is a privileged structure in medicinal chemistry for designing bioactive molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on synthesizing novel kinase inhibitors, receptor modulators, and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in drug discovery programs, especially for kinase and enzyme inhibition studies.
• Agrochemical Development: Used in the research and synthesis of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Employed in the development of molecular probes to study biological processes and protein functions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and custom synthesis houses to produce more complex, target-specific molecules for clients.

Basic Information

Product Name	Methyl 5-Chloro-1H-Indazole-3-Carboxylate
CAS No.	1079-46-5
Molecular Formula	C9H7ClN2O2
Molecular Weight	210.62 g/mol
Synonyms	5-Chloro-1H-indazole-3-carboxylic acid methyl ester; Methyl 5-chloroindazole-3-carboxylate; 3-Methoxycarbonyl-5-chloroindazole; 5-Chloroindazole-3-carboxylic acid methyl ester; 1H-Indazole-3-carboxylic acid, 5-chloro-, methyl ester; 1079-46-5
EINECS	Contact for details

Quality Control

Our Methyl 5-Chloro-1H-Indazole-3-Carboxylate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.