Description

6-Benzyl-2-(Methylthio)-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidin-4-Ol is a high-purity heterocyclic organic compound that serves as a critical advanced intermediate in modern pharmaceutical synthesis. Its value lies in its role as a versatile building block for the development of novel therapeutic agents, particularly in kinase inhibitor research. This product is essential for R&D chemists and process development scientists in the pharmaceutical and biotechnology industries working on innovative drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of targeted kinase inhibitors and other small-molecule drugs.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Process Chemistry Development: Employed in route scouting, scale-up studies, and the development of robust commercial manufacturing processes for active pharmaceutical ingredients (APIs).
• Biochemical Tool Compound: Serves as a starting material for synthesizing labeled analogs or probes for biological target validation and mechanism-of-action studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global pharmaceutical clients with custom synthesis and development services.

Basic Information

Product Name	6-Benzyl-2-(Methylthio)-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidin-4-Ol
CAS No.	1033-34-7
Molecular Formula	C₁₆H₁₉N₃OS
Molecular Weight	301.41 g/mol
Synonyms	6-Benzyl-2-(methylthio)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-ol; 6-Benzyl-2-methylsulfanyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-ol; 2-(Methylthio)-6-benzyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-ol; 1033-34-7; Pyrido[4,3-d]pyrimidin-4-ol, 6-benzyl-2-(methylthio)-5,6,7,8-tetrahydro-; 6-Benzyl-2-methylmercapto-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-one (tautomer); Benzyl-MT-THPP
EINECS	Contact for details

Quality Control

Our production of 6-Benzyl-2-(Methylthio)-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidin-4-Ol adheres to stringent quality management systems, ensuring batch-to-batch consistency suitable for demanding pharmaceutical R&D. All materials are characterized by advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.