Description

5-Bromo-2'-Deoxycytidine is a halogenated nucleoside analog of significant importance in biochemical and pharmaceutical research. This modified nucleoside serves as a critical building block for the synthesis of oligonucleotides and probes used in molecular biology and diagnostic applications. It is primarily utilized by researchers and manufacturers in the fields of antiviral drug discovery, genetic research, and diagnostic assay development.

Application

• Antiviral and Anticancer Nucleoside Analog Synthesis: A key intermediate in the research and development of novel therapeutic agents.
• Oligonucleotide Synthesis: Used to incorporate brominated bases into DNA strands for structural studies, cross-linking experiments, and probe development.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies involving DNA polymerases, nucleoside kinases, and other nucleic acid metabolizing enzymes.
• Diagnostic Probe Development: Facilitates the creation of labeled nucleotides for use in hybridization assays and other molecular diagnostic techniques.
• Chemical Biology Tool: Acts as a versatile building block for studying DNA damage, repair mechanisms, and epigenetic modifications.

Basic Information

Product Name	5-Bromo-2'-Deoxycytidine
CAS No.	1022-79-3
Molecular Formula	C9H12BrN3O4
Molecular Weight	306.11 g/mol
Synonyms	5-Bromo-2'-deoxycytidine; 5-Bromo-2'-deoxycytidine; 5-Br-dC; 5-Bromodeoxycytidine; 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-bromocytosine; 5-Bromo-1-(2-deoxy-β-D-ribofuranosyl)cytosine; 2'-Deoxy-5-bromocytidine; NSC 38297
EINECS	Contact for details

Quality Control

Our 5-Bromo-2'-Deoxycytidine is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.