Description

2,6-Diamino-5-(β-D-Glucopyranosyloxy)-(1H)-Pyrimidin-4-One is a nucleoside analog with a unique pyrimidine base linked to a glucose moiety. This compound is of significant interest in biochemical and pharmaceutical research due to its structural similarity to natural nucleosides. It serves as a key intermediate and reference standard for researchers in medicinal chemistry, enzymology, and the development of novel therapeutic agents.

Application

• Pharmaceutical Research & Development: As a critical building block or reference standard in the synthesis of novel nucleoside-based drugs, antivirals, and enzyme inhibitors.
• Biochemical Studies: Used as a substrate or inhibitor in enzymatic assays to study nucleoside-metabolizing enzymes like kinases and phosphorylases.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Academic Research: Employed in universities and research institutes for fundamental studies on nucleic acid chemistry and metabolic pathways.
• Diagnostic Reagent Development: Potential use in the formulation of diagnostic kits or assays that detect specific enzymatic activities.
• Process Development & Scale-up: Used by CROs and CDMOs to develop and optimize synthetic routes for GMP production.

Basic Information

Item	Details
Product Name	2,6-Diamino-5-(β-D-Glucopyranosyloxy)-(1H)-Pyrimidin-4-One
CAS No.	152-93-2
Molecular Formula	C10H16N4O7
Molecular Weight	304.26 g/mol
Synonyms	5-Glucosyloxy-2,6-diaminopyrimidin-4(1H)-one; 2,6-Diamino-5-(β-D-glucopyranosyloxy)-4(1H)-pyrimidinone; 5-(β-D-Glucopyranosyloxy)-2,6-diamino-4(1H)-pyrimidinone; 2,6-Diamino-5-(β-D-glucosyloxy)-4-pyrimidinol; Glucosyloxy-diaminopyrimidinone; Nucleoside analog intermediate; CAS 152-93-2
EINECS	Contact for details

Quality Control

We supply high-purity material suitable for research and development applications. Every batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR). A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to ensure traceability and meet your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.