Description

Butacaine Sulphate is a potent local anesthetic agent, primarily recognized for its surface numbing properties. It is valued in pharmaceutical manufacturing for its reliable and rapid onset of action, providing effective topical anesthesia. This compound is essential for formulators and producers in the pharmaceutical and medical device industries, where it is used to develop topical creams, ointments, and ophthalmic solutions.

Application

• Topical Anesthetic Formulations: Key ingredient in creams, gels, and ointments for temporary relief of pain and itching.
• Ophthalmic Solutions: Used in eye drops for surface anesthesia during minor ocular procedures and examinations.
• Dermatological Preparations: Incorporated into products for pre-injection skin numbing or treatment of minor skin irritations.
• Veterinary Medicine: Employed in topical preparations for animal healthcare.
• Analgesic Stick Formulations: Used in solid applicators for targeted pain relief.
• Pharmaceutical Intermediates: Serves as a chemical building block in the synthesis of more complex anesthetic agents.
• Research & Development: Used as a reference standard and in pharmacological studies of local anesthetic mechanisms.

Basic Information

Product Name	Butacaine Sulphate
CAS No.	149-15-5
Molecular Formula	C18H30N2O2 · H2SO4
Molecular Weight	402.52 g/mol
Synonyms	Butacaine Sulfate; Butyn Sulfate; 3-(Dibutylamino)propyl 4-aminobenzoate sulfate; Butelline; Butoforme; Butyn (sulfate salt); p-Aminobenzoic acid 3-(dibutylamino)propyl ester sulfate; 4-Aminobenzoic acid 3-(dibutylamino)propyl ester sulfate (1:1)
EINECS	205-734-6

Quality Control

Our Butacaine Sulphate is manufactured under strict quality systems to ensure it meets the stringent requirements for pharmaceutical use. Each batch is tested against comprehensive specifications, including identity, purity, and impurity profiles. Certificates of Analysis (COA) are provided with every shipment, detailing results from advanced analytical techniques like HPLC. We can supply material compliant with various pharmacopeial standards, including USP, upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Specific Rotation	Contact for details
pH (Solution)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.