Description

2-Bromoadenosine is a halogenated nucleoside derivative of adenosine, serving as a crucial building block and research chemical in life sciences. Its primary value lies in its role as a versatile intermediate for the synthesis of modified nucleotides and potential pharmaceutical agents. This compound is essential for researchers and manufacturers in pharmaceutical development, biochemical research, and nucleotide chemistry, where precise molecular modifications are required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel adenosine receptor ligands and antiviral/anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving kinases, phosphorylases, and other adenosine-metabolizing enzymes.
• Probe Development: Serves as a starting material for creating fluorescent or affinity-labeled probes to study nucleic acid interactions and cellular processes.
• Nucleotide Chemistry: Fundamental building block for solid-phase oligonucleotide synthesis to incorporate modified bases for structure-activity relationship (SAR) studies.
• Academic & Industrial R&D: Employed in medicinal chemistry programs for drug discovery targeting purinergic signaling pathways.

Basic Information

Product Name	2-Bromoadenosine
CAS No.	146-76-9
Molecular Formula	C10H12BrN5O4
Molecular Weight	346.14 g/mol
Synonyms	2-Bromo-9-β-D-ribofuranosyl-9H-purin-6-amine; 2-Bromoadenosine; Adenosine, 2-bromo-; 2-Br-Ado; 2-Bromo-adenosine; 9-β-D-Ribofuranosyl-2-bromoadenine; 2-Bromo-9-β-D-ribofuranosyladenine
EINECS	205-683-6

Quality Control

Our 2-Bromoadenosine is produced and tested under a rigorous quality management system. Each batch is analyzed to ensure high chemical purity and identity, with specifications suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.