Description

14,21-Epoxy-3β,5-Dihydroxy-19-Oxo-5β-Cardanolide is a high-purity, specialized cardanolide derivative, a key structural motif in bioactive natural products. This compound is valued for its role as a critical advanced pharmaceutical intermediate and a versatile scaffold in organic synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel cardiac glycosides and other steroidal drugs.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new bioactive molecules.
• Reference Standard: Employed as an analytical standard in quality control laboratories for the identification and quantification of related compounds.
• Organic Synthesis: Acts as a versatile chiral starting material for the synthesis of complex natural products and specialty fine chemicals.
• Biochemical Research: Investigated for its interaction with biological targets such as Na+/K+-ATPase, relevant to cardiovascular and cancer research.

Basic Information

Item	Detail
Product Name	14,21-Epoxy-3β,5-Dihydroxy-19-Oxo-5β-Cardanolide
CAS No.	143-58-8
Molecular Formula	C₂₃H₃₂O₆
Molecular Weight	404.50 g/mol
Synonyms	19-Oxocardenolide; 3β,5-Dihydroxy-14,21-epoxy-19-oxo-5β-card-20(22)-enolide; 19-Oxocarden; 14,21-Epoxy-3β,5-dihydroxy-19-oxo-5β,14β-card-20(22)-enolide; 3β,5-Dihydroxy-14β,21-epoxy-19-oxo-5β-card-20(22)-enolide; 19-Oxo-3β,5,14-trihydroxy-5β-card-20(22)-enolide 14,21-ether
EINECS	Contact for details

Quality Control

Our 14,21-Epoxy-3β,5-Dihydroxy-19-Oxo-5β-Cardanolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.