Description

2,4,6-Collidine is a versatile alkylated pyridine derivative, valued for its role as a sterically hindered base and a key building block in organic synthesis. Its unique substitution pattern makes it an essential reagent for modulating reaction conditions and synthesizing complex molecules. This high-purity intermediate is critical for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Synthesis: Employed as a base and catalyst in the production of active pharmaceutical ingredients (APIs), particularly for reactions requiring a non-nucleophilic, hindered amine.
• Agrochemical Manufacturing: Serves as a key intermediate in the synthesis of advanced crop protection agents and herbicides.
• Chemical Research & Development: A fundamental reagent in organic synthesis labs for deprotonation reactions, ligand synthesis, and as a precursor for more complex heterocyclic compounds.
• Coordination Chemistry: Used as a ligand for metal complexes in catalysis and materials science applications.
• Specialty Polymers & Materials: Acts as a monomer or modifier in the development of advanced polymeric materials with specific properties.

Basic Information

Product Name	2,4,6-Collidine
CAS No.	108-75-8
Molecular Formula	C8H11N
Molecular Weight	121.18 g/mol
Synonyms	2,4,6-Trimethylpyridine; sym-Collidine; γ-Collidine; 2,4,6-Trimethylazine; NSC 9376; TMPy
EINECS	203-613-4

Quality Control

Our 2,4,6-Collidine is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure it meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong oxidizing agents. Recommended storage temperature is 15-25°C. Keep container tightly sealed when not in use to prevent moisture absorption and quality degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.5%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.