Aminoglycosides

Aminoglycosides

Aminoglycosides are broad-spectrum bactericidal APIs that inhibit bacterial protein synthesis by binding to the 30S ribosomal subunit, causing misreading of mRNA and blocking peptide elongation. Common agents include gentamicin, amikacin, tobramycin, and streptomycin. They are especially effective against aerobic Gram-negative bacteria and are widely used in sepsis, pneumonia, complicated urinary infections, and tuberculosis regimens. Aminoglycosides exhibit concentration-dependent killing and strong post-antibiotic effects. However, nephrotoxicity and ototoxicity require therapeutic drug monitoring. Their formulations include injectables, inhalation solutions, and topical preparations for ophthalmic and dermatologic infections. Aminoglycosides remain essential in severe infections despite safety considerations.

4-o-(2-Amino-2-Deoxy-Α-D-Glucopyranosyl)-5-o-Β-D-Xylofuranosyl-n-[(S)-4-Amino-2-Hydroxybutyryl]-2-Deoxy-D-Streptamine CAS NO 54333-82-3

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CAS No.:54333-82-3

Grade:Pharmacy Grade

Content:99.90%

Packaging:Customizable

Fortimicin B CAS NO 54783-95-8

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CAS No.:54783-95-8

Grade:Pharmacy Grade

Content:99.90%

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5''-Amino-4',5''-Dideoxybutirosin A CAS NO 55480-22-3

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CAS No.:55480-22-3

Grade:Pharmacy Grade

Content:99.90%

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4-o-(2-Amino-2-Deoxy-Α-D-Glucopyranosyl)-5-o-(Β-D-Xylofuranosyl)-2-Deoxy-D-Streptamine CAS NO 55484-62-3

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CAS No.:55484-62-3

Grade:Pharmacy Grade

Content:99.90%

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Gentamicin A3 CAS NO 55715-67-8

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CAS No.:55715-67-8

Grade:Pharmacy Grade

Content:99.90%

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Fortimicin CAS NO 55779-06-1

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CAS No.:55779-06-1

Grade:Pharmacy Grade

Content:99.90%

Packaging:Customizable

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