Description

Ethyl Bromofluoroacetate is a versatile fluorinated building block and alkylating agent of significant importance in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents on the acetate backbone, makes it a critical reagent for introducing fluorinated moieties into complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty materials industries, enabling the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), including potential antiviral and anticancer agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides where the fluorine atom enhances biological activity and environmental stability.
• Fluorinated Material Precursor: Serves as a monomer or modifier in the synthesis of specialty polymers, liquid crystals, and electronic materials.
• Organic Synthesis Reagent: Employed in nucleophilic substitution and esterification reactions to incorporate the -CHFCOOEt group into target molecules.
• PET (Positron Emission Tomography) Tracer Development: Potential precursor for radiolabeling compounds used in medical imaging.
• Chemical Biology Probe Synthesis: Useful for creating fluorinated analogs of biomolecules to study enzyme mechanisms and metabolic pathways.

Basic Information

Item	Details
Product Name	Ethyl Bromofluoroacetate
CAS No.	401-55-8
Molecular Formula	C4H6BrFO2
Molecular Weight	184.99 g/mol
Synonyms	Bromofluoroacetic Acid Ethyl Ester; Ethyl 2-Bromo-2-fluoroacetate; 2-Bromo-2-fluoroacetic Acid Ethyl Ester; Monofluoroethyl Bromoacetate; Ethyl α-Bromo-α-fluoroacetate; Bromo(fluoro)acetic Acid Ethyl Ester; FAEBA; Contact for additional synonyms
EINECS	206-934-9

Quality Control

Our Ethyl Bromofluoroacetate is produced and tested under a strict quality management system. Each batch undergoes comprehensive analysis to ensure high purity and consistency, meeting the exacting standards required for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as oxidizing agents. Due to its sensitivity, it is recommended to store under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.6 g/mL
Refractive Index (n20D)	~1.42 - 1.44

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.