Description

(1S,2R,4'aβ,6S,7'S,9a'S)-6-(Acetyloxy)-4'a,5',6',7',8',9'-hexahydro-5'α-hydroxy-3,3-dimethyl-8'-methylene-1',9'-dioxospiro[cyclohexane-1,4'(3'H)-[1H-7,9a]methanocyclohepta[c]pyran]-2-carbaldehyde is a complex, high-purity synthetic intermediate characterized by its unique spirocyclic and polycyclic architecture. This compound is of significant value in advanced organic synthesis, particularly for constructing intricate molecular scaffolds found in active pharmaceutical ingredients (APIs) and specialty fine chemicals. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced material sectors for its utility as a key chiral building block.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of novel drug candidates, particularly for complex target molecules.
• Agrochemical Research: Used in the development of advanced, biologically active compounds with specific stereochemical requirements.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex polycyclic and spirocyclic frameworks.
• Process Chemistry: Acts as a starting material or intermediate in the scale-up and optimization of synthetic routes for high-value chemicals.
• Material Science Research: Potential use in the synthesis of specialized organic molecules for advanced material applications.

Basic Information

Product Name	(1S,2R,4'aβ,6S,7'S,9a'S)-6-(Acetyloxy)-4'a,5',6',7',8',9'-hexahydro-5'α-hydroxy-3,3-dimethyl-8'-methylene-1',9'-dioxospiro[cyclohexane-1,4'(3'H)-[1H-7,9a]methanocyclohepta[c]pyran]-2-carbaldehyde
CAS No.	92533-54-5
Molecular Formula	C23H28O7
Molecular Weight	416.47 g/mol
Synonyms	6-Acetoxy-5'-hydroxy-3,3-dimethyl-8'-methylenespiro[cyclohexane-1,4'(3'H)-[1H-7,9a]methanocyclohepta[c]pyran]-1',9'-dione-2-carboxaldehyde; Spiro[cyclohexane-1,4'(3'H)-[1H-7,9a]methanocyclohepta[c]pyran]-2-carbaldehyde derivative; CAS 92533-54-5; 92533-54-5; 6-(Acetyloxy)-4'a,5',6',7',8',9'-hexahydro-5'α-hydroxy-3,3-dimethyl-8'-methylene-1',9'-dioxospiro[cyclohexane-1,4'(3'H)-[1H-7,9a]methanocyclohepta[c]pyran]-2-carbaldehyde
EINECS	Contact for details

Quality Control

Our (1S,2R,4'aβ,6S,7'S,9a'S)-6-(Acetyloxy)-4'a,5',6',7',8',9'-hexahydro-5'α-hydroxy-3,3-dimethyl-8'-methylene-1',9'-dioxospiro[cyclohexane-1,4'(3'H)-[1H-7,9a]methanocyclohepta[c]pyran]-2-carbaldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), chiral purity, and impurity profiles are provided to guarantee it meets the exacting standards required for research and process development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). For long-term storage, consider storage under an inert gas such as argon or nitrogen in a sealed container.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.