Description

Benzyl 5-Azaspiro[2.5]Octane-5-Carboxylate is a high-value, spirocyclic organic building block of significant interest in advanced pharmaceutical and agrochemical research. Its unique structural motif, featuring a spiro-fused azetidine and cyclopropane ring system, makes it a critical intermediate for synthesizing novel bioactive molecules. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical industry for constructing complex molecular architectures, particularly in drug discovery programs targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those with spirocyclic or constrained structures.
• Medicinal Chemistry Research: Used in the exploration of structure-activity relationships (SAR) to develop new therapeutic agents with improved potency and selectivity.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides and herbicides with novel modes of action.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Process Chemistry & Scale-up: Employed in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Academic & Institutional Research: A valuable reagent for universities and research institutes conducting cutting-edge synthetic organic chemistry.

Basic Information

Product Name	Benzyl 5-Azaspiro[2.5]Octane-5-Carboxylate
CAS No.	1454650-21-5
Molecular Formula	C15H19NO2
Molecular Weight	245.32 g/mol
Synonyms	Benzyl 5-azaspiro[2.5]octane-5-carboxylate; 5-[(Benzyloxy)carbonyl]-5-azaspiro[2.5]octane; 5-Azaspiro[2.5]octane-5-carboxylic acid benzyl ester; 5-CBz-5-azaspiro[2.5]octane; 5-Benzyloxycarbonyl-5-azaspiro[2.5]octane; 5-Azaspiro[2.5]octane, 5-(phenylmethoxy)carbonyl-; Benzyl 5-azaspiro[2.5]octane-5-carboxylate (CAS 1454650-21-5)
EINECS	Contact for details

Quality Control

Our Benzyl 5-Azaspiro[2.5]Octane-5-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key analytical parameters. Our quality management system adheres to cGMP principles where applicable, ensuring traceability and reliability for critical pharmaceutical supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.