Description

(3R,5S,7R,8S,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-5,6,7-trihydroxyheptan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol is a high-purity, complex sterol derivative with significant potential in advanced research and development. This compound matters as a critical reference standard and pharmaceutical intermediate for the synthesis and study of bioactive molecules. It is primarily needed by research institutions and pharmaceutical companies focused on steroid chemistry, metabolic pathway analysis, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of complex steroid-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or probe in metabolic studies, enzyme inhibition assays, and receptor binding research.
• Analytical Standard: Provides a high-purity benchmark for method development and quality control in analytical laboratories using HPLC, LC-MS, or NMR.
• Academic Research: Facilitates studies in organic synthesis, stereochemistry, and the structure-activity relationships (SAR) of steroidal compounds.
• Preclinical Development: Employed in the early-stage development of new chemical entities (NCEs) targeting hormonal or metabolic pathways.

Basic Information

Item	Details
Product Name	(3R,5S,7R,8S,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-5,6,7-trihydroxyheptan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol
CAS No.	91999-66-5
Molecular Formula	C27H46O6
Molecular Weight	466.66 g/mol
Synonyms	3β,7α,12α-Trihydroxy-5β-cholestan-26-oic acid (lactone form derivative); 5β-Cholestane-3β,7α,12α,26-tetrol lactone isomer; Tetrahydroxycholestane lactone; Sterol triol lactone derivative; (25R)-3α,7α,12α-Trihydroxy-5β-cholestan-26-oic acid δ-lactone (related isomer); 26-Nor-5β-cholestane-3β,7α,12α,25-tetrol γ-lactone (structural variant); Cholestanetriol heptanoate derivative
EINECS	Contact for details

Quality Control

Our (3R,5S,7R,8S,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-5,6,7-trihydroxyheptan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. Certificates of Analysis (COA) detailing all specifications and test results are available upon request to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.