Description

1,4-Methanonaphthalene,9-Fluoro-1,2,3,4-Tetrahydro-,Stereoisomer(9Ci) is a high-purity, stereochemically defined fluorinated organic building block of significant interest in advanced chemical synthesis. This compound is valued for its unique bridged polycyclic structure, which serves as a critical scaffold for developing novel pharmacologically active molecules and functional materials. It is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry, catalysis, and material science.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology drug discovery programs.
• Agrochemical Research: Used as a sophisticated building block in the synthesis of novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Catalyst & Ligand Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Precursor: Employed in the synthesis of advanced organic electronic materials, liquid crystals, and polymers with specific fluorinated properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including cycloaddition reactions and fluorination chemistry.

Basic Information

Product Name	1,4-Methanonaphthalene,9-Fluoro-1,2,3,4-Tetrahydro-,Stereoisomer(9Ci)
CAS No.	181876-54-0
Molecular Formula	C₁₅H₁₅F
Molecular Weight	214.28 g/mol
Synonyms	9-Fluoro-1,2,3,4-tetrahydro-1,4-methanonaphthalene; 9-Fluoro-1,4-methano-1,2,3,4-tetrahydronaphthalene; Fluorinated 1,4-methanonaphthalene derivative; Bridged fluoronaphthalene; (1R,4S)-9-Fluoro-1,2,3,4-tetrahydro-1,4-methanonaphthalene (for specific stereoisomer); (1S,4R)-9-Fluoro-1,2,3,4-tetrahydro-1,4-methanonaphthalene (for specific stereoisomer); CAS 181876-54-0.
EINECS	Contact for details

Quality Control

Our 1,4-Methanonaphthalene,9-Fluoro-1,2,3,4-Tetrahydro-,Stereoisomer(9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity, typically exceeding 97% (by HPLC). Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, stereochemical identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality management system is designed to meet the stringent requirements of pharmaceutical and advanced R&D customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to strong bases and fluorides, keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation (Optical Purity)	Provided on COA
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.