Description

L-Threonine,(3R)-N-acetyl-3-hydroxy-L-leucyl-(aR)-a-hydroxybenzenepropanoyl-2,3-didehydro-N-methylalanyl-L-alanyl-N-methyl-L-alanyl-(3R)-3-[[(2S,3R)-3-hydroxy-4-methyl-1-oxo-2-[(1-oxopropyl)amino]pentyl]oxy]-L-leucyl-N,O-dimethyl-,(7(R)1)-lactone (9CI) is a complex, cyclic depsipeptide derivative of significant interest in advanced pharmaceutical research and development. This compound matters as a sophisticated chemical entity, often serving as a key intermediate or a structural motif in the synthesis of novel bioactive molecules, particularly in the field of peptide-based therapeutics. Industries that need this high-purity specialty chemical include pharmaceutical R&D, biotechnology firms, and academic research institutions focused on oncology, antimicrobial agents, and targeted drug delivery systems.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of complex peptide-based active pharmaceutical ingredients (APIs).
• Research & Development: Used as a reference standard or a key reactant in medicinal chemistry programs for developing new therapeutic candidates.
• Bioconjugation Studies: Its functional groups make it suitable for exploring novel bioconjugation techniques in drug delivery system design.
• Chemical Biology Probes: Utilized in the development of specialized probes to study enzyme mechanisms or protein-protein interactions.
• Process Development: Employed in scaling up and optimizing synthetic routes for novel peptide-derived compounds in pilot plants.

Basic Information

Item	Details
Product Name	L-Threonine,(3R)-N-acetyl-3-hydroxy-L-leucyl-(aR)-a-hydroxybenzenepropanoyl-2,3-didehydro-N-methylalanyl-L-alanyl-N-methyl-L-alanyl-(3R)-3-[[(2S,3R)-3-hydroxy-4-methyl-1-oxo-2-[(1-oxopropyl)amino]pentyl]oxy]-L-leucyl-N,O-dimethyl-,(7(R)1)-lactone (9CI)
CAS No.	107530-18-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cyclic Depsipeptide 107530-18-7; N-Acetyl-3-hydroxy-L-leucyl-a-hydroxybenzenepropanoyl-2,3-didehydro-N-methylalanyl-L-alanyl-N-methyl-L-alanyl-3-[[3-hydroxy-4-methyl-1-oxo-2-[(1-oxopropyl)amino]pentyl]oxy]-L-leucyl-N,O-dimethyl-lactone; (3R)-N-acetyl-3-hydroxy-L-leucyl-(aR)-a-hydroxybenzenepropanoyl-2,3-didehydro-N-methylalanyl-L-alanyl-N-methyl-L-alanyl-(3R)-3-[[(2S,3R)-3-hydroxy-4-methyl-1-oxo-2-[(1-oxopropyl)amino]pentyl]oxy]-L-leucyl-N,O-dimethyl-,(7(R)1)-lactone; L-Threonine derivative lactone; Complex Peptide Lactone; 9CI Identifier Compound
EINECS	Contact for details

Quality Control

Our L-Threonine,(3R)-N-acetyl-3-hydroxy-L-leucyl-(aR)-a-hydroxybenzenepropanoyl-2,3-didehydro-N-methylalanyl-L-alanyl-N-methyl-L-alanyl-(3R)-3-[[(2S,3R)-3-hydroxy-4-methyl-1-oxo-2-[(1-oxopropyl)amino]pentyl]oxy]-L-leucyl-N,O-dimethyl-,(7(R)1)-lactone (9CI) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be incompatible with strong acids and organic solvents; store separately from such materials. For long-term stability, consider storage under an inert atmosphere if the material is found to be easily oxidized.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.