Description

2-(4-Phenylpiperazino)-1,3-Thiazole-5-Carbaldehyde is a high-value heterocyclic building block featuring a thiazole core substituted with a phenylpiperazine moiety and an aldehyde functional group. This compound is critical for medicinal chemistry research and pharmaceutical development, serving as a versatile precursor for synthesizing novel bioactive molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating libraries of potential drug candidates and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small-molecule therapeutics targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new pharmacophores and optimize lead compounds.
• Agrochemical Synthesis: Serves as a building block for creating new active ingredients for crop protection products, such as fungicides or insecticides.
• Chemical Biology Probes: The reactive aldehyde group allows for conjugation, making it useful in developing chemical probes for studying biological pathways and protein interactions.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	2-(4-Phenylpiperazino)-1,3-Thiazole-5-Carbaldehyde
CAS No.	303987-39-5
Molecular Formula	C14H15N3OS
Molecular Weight	273.35 g/mol
Synonyms	2-(4-Phenyl-1-piperazinyl)-1,3-thiazole-5-carboxaldehyde; 5-Formyl-2-(4-phenylpiperazin-1-yl)-1,3-thiazole; 2-(4-Phenylpiperazin-1-yl)thiazole-5-carbaldehyde; 303987-39-5; Thiazole-5-carbaldehyde, 2-(4-phenyl-1-piperazinyl)-; AKOS005158625; 1,3-Thiazole-5-carboxaldehyde, 2-(4-phenyl-1-piperazinyl)-
EINECS	Contact for details

Quality Control

Our 2-(4-Phenylpiperazino)-1,3-Thiazole-5-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.