Description

[3-[[3-[[5-(2-amino-6-oxo-3H-purin-9-yl)-3-hydroxy-oxolan-2-yl]oxy-hydroxy-phosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)oxolan-2-yl]methoxy-[5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl]oxy-phosphinic acid, azane, azanide, platinum(+2) cation is a complex platinum coordination compound designed for advanced pharmaceutical research and development. This compound is of significant interest for its potential role as a novel chemotherapeutic agent or a key intermediate in the synthesis of targeted cancer therapies. It is primarily utilized by pharmaceutical R&D laboratories and academic research institutions focused on oncology and medicinal chemistry.

Application

• Pharmaceutical Research: As a potential active pharmaceutical ingredient (API) or precursor in the development of next-generation platinum-based anticancer drugs.
• Medicinal Chemistry: Serving as a key intermediate for the synthesis of novel nucleotide-platinum conjugates designed for targeted drug delivery.
• Biochemical Research: Used in studies investigating the interaction mechanisms of platinum complexes with DNA and other biological targets.
• Oncology Drug Discovery: Evaluation of cytotoxicity and efficacy against various cancer cell lines in preclinical studies.
• Process Development: Optimization of synthesis and purification scales for potential Good Manufacturing Practice (GMP) production.

Basic Information

Product Name	[3-[[3-[[5-(2-amino-6-oxo-3H-purin-9-yl)-3-hydroxy-oxolan-2-yl]oxy-hydroxy-phosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)oxolan-2-yl]methoxy-[5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl]oxy-phosphinic acid, azane, azanide, platinum(+2) cation
CAS No.	91864-32-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Platinum nucleotide complex; Platinum(II) nucleotide conjugate; Platinum-adenosine-guanosine-thymidine conjugate; Anticancer platinum nucleotide; Platinum-DNA binding agent; Research compound 91864-32-3; Platinum nucleoside phosphate complex
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research chemicals. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and stability. Certificates of Analysis (COA) are available upon request, detailing specifications such as assay purity by HPLC, identification by spectroscopic methods, and impurity profiles. We adhere to a strict quality management system to ensure batch-to-batch consistency for your critical research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals (Platinum)	Reported

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.