Description

Melphalan is a nitrogen mustard derivative and a potent bifunctional alkylating agent used in chemotherapy. Its primary value lies in its ability to crosslink DNA, inhibiting the replication of rapidly dividing cells, which makes it a critical component in specific oncology treatment protocols. This product is essential for pharmaceutical manufacturers, research institutions, and laboratories engaged in the development and production of chemotherapeutic agents, particularly for the treatment of conditions such as multiple myeloma and ovarian carcinoma.

Application

• Active Pharmaceutical Ingredient (API) in the formulation of injectable and oral chemotherapeutic drugs.
• Key intermediate in the synthesis of more complex, targeted anti-cancer agents and prodrugs.
• Reference standard in analytical laboratories for quality control and method validation of pharmaceutical products.
• Critical reagent in preclinical and clinical research studies investigating alkylating agent mechanisms and efficacy.
• Used in biochemical research to study DNA damage, cell cycle arrest, and apoptosis pathways.
• Component in the development of combination chemotherapy regimens and novel drug delivery systems.

Basic Information

Item	Detail
Product Name	Melphalan
CAS No.	1465-26-5
Molecular Formula	C13H18Cl2N2O2
Molecular Weight	305.20 g/mol
Synonyms	L-Phenylalanine mustard; L-Sarcolysin; Alkeran; CB-3025; NSC-8806; 4-[bis(2-chloroethyl)amino]-L-phenylalanine; (2S)-2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid
EINECS	Contact for details

Quality Control

Our Melphalan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We adhere to relevant guidelines for active pharmaceutical ingredients (APIs).

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) or as specified on the label. Due to its sensitivity to light and oxidation, the container should only be opened in a controlled environment and material should be used promptly.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.