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n-[1-[Bis(2-Chloroethyl)Carbamoyl]Ethyl]Benzamide CAS NO 1462-81-3
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CAS No.:1462-81-3
Grade:Pharmacy Grade
Content:99.0%
Brand:Customizable
Packaging:Customizable
Description
n-[1-[Bis(2-Chloroethyl)Carbamoyl]Ethyl]Benzamide is a specialized nitrogen mustard derivative with a carbamoyl benzamide structure, primarily valued as a key synthetic intermediate in advanced pharmaceutical research and development. Its molecular architecture, featuring reactive bis(2-chloroethyl) groups, makes it a critical precursor for constructing complex molecules with targeted biological activity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly those developing novel alkylating agents, targeted therapies, and other bioactive compounds.
Application
- Pharmaceutical Intermediate: A crucial building block in the synthesis of nitrogen mustard-based chemotherapeutic agents and targeted cancer therapies.
- Alkylating Agent Precursor: Used in research to develop novel alkylating compounds for studying DNA interaction and cytotoxicity mechanisms.
- Medicinal Chemistry Research: Serves as a key scaffold in drug discovery programs for creating libraries of potential bioactive molecules.
- Agrochemical Synthesis: Employed in the development of advanced pesticides and herbicides that require specific alkylating functionalities.
- Biochemical Probe Development: Utilized to create molecular probes for investigating enzyme inhibition and cellular signaling pathways.
- Polymer Modification: Acts as a cross-linking or functionalizing agent in the synthesis of specialty polymers with specific reactive sites.
Basic Information
| Product Name | n-[1-[Bis(2-Chloroethyl)Carbamoyl]Ethyl]Benzamide |
| CAS No. | 1462-81-3 |
| Molecular Formula | C₁₄H₁₈Cl₂N₂O₂ |
| Molecular Weight | 317.21 g/mol |
| Synonyms | Benzamide, N-[1-[[bis(2-chloroethyl)amino]carbonyl]ethyl]-; 2-[(2-Chloroethyl)(2-{[(2-chloroethyl)amino]carbonyl}ethyl)amino]-N-phenylacetamide (alternative representation); NSC 82116; Uracil Mustard analog intermediate; Nitrogen mustard benzamide derivative; Carbamoyl mustard intermediate; 1-(Bis(2-chloroethyl)carbamoyl)ethyl benzamide |
| EINECS | Contact for details |
Quality Control
Our n-[1-[Bis(2-Chloroethyl)Carbamoyl]Ethyl]Benzamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment to support your regulatory and research documentation needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. This material is light-sensitive (store away from light).
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥ 98.0% |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 10 ppm |
| Related Substances (HPLC) | Individual impurity ≤ 0.5%, Total impurities ≤ 2.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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