Description

Oxaliplatin is a third-generation platinum-based antineoplastic agent, a cornerstone in modern chemotherapy regimens. Its primary value lies in its distinct mechanism of action, which provides efficacy against tumors that may be resistant to other platinum compounds. This high-purity active pharmaceutical ingredient (API) is essential for pharmaceutical manufacturers and research institutions developing and producing life-saving oncology treatments, particularly for colorectal cancer.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable chemotherapy formulations.
• First-line Colorectal Cancer Therapy: Key component in the FOLFOX (folinic acid, fluorouracil, and oxaliplatin) and XELOX (capecitabine and oxaliplatin) treatment protocols.
• Adjuvant & Metastatic Treatment: Used in both post-surgical adjuvant therapy and for treating metastatic disease.
• Oncology Research: Serves as a critical reference standard and investigational compound in preclinical and clinical cancer research.
• Drug Combination Studies: Used in research exploring synergistic effects with other chemotherapeutic agents or targeted therapies.
• Formulation Development: Employed in the development of novel drug delivery systems, such as liposomal or nanoparticle-based formulations.

Basic Information

Product Name	Oxaliplatin
CAS No.	61825-94-3
Molecular Formula	C8H14N2O4Pt
Molecular Weight	397.29 g/mol
Synonyms	1,2-Diaminocyclohexane oxalatoplatinum; Eloxatin®; Dacplat; RP 54780; L-OHP; Oxalatoplatinum; (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-N,N'] [oxalato(2-)-O,O'] platinum
EINECS	Contact for details

Quality Control

Our Oxaliplatin is manufactured under strict quality management systems. It undergoes comprehensive analytical testing to ensure it meets stringent pharmacopeial standards for identity, purity, and potency. A detailed Certificate of Analysis (COA) is provided with each batch, confirming compliance with specifications for Assay, related substances, residual solvents, and heavy metals. We support compliance with cGMP, ICH Q7, and other relevant regulatory guidelines for pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.