Description

(2'aR,3S,5S,9'aR)-5-(3-Furanyl)-2'a,3',4,5,5',5'aα,8',9'-octahydro-4'α,9'α-dihydroxy-2'a-(hydroxymethyl)-7'β-methylspiro[furan-3(2H),6'(7'H)-[4H]naphth[1,8a-b]oxet]-2-one CAS NO 87587-49-3 is a complex, high-purity spirocyclic organic compound featuring a unique naphthoxetane-furan fused ring system. This compound is of significant interest for its potential as a key chiral intermediate or pharmacophore in advanced pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block for the synthesis of potential new chemical entities (NCEs) targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for drug discovery programs.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of complex target molecules.
• Agrochemical Synthesis: Potential intermediate in the development of new, high-value crop protection agents with specific modes of action.
• Academic Research: Utilized in universities and research institutes for studies in organic synthesis methodology and natural product analog development.
• Fine Chemical Production: Acts as a specialty intermediate for custom synthesis and contract manufacturing projects.

Basic Information

Item	Detail
Product Name	(2'aR,3S,5S,9'aR)-5-(3-Furanyl)-2'a,3',4,5,5',5'aα,8',9'-octahydro-4'α,9'α-dihydroxy-2'a-(hydroxymethyl)-7'β-methylspiro[furan-3(2H),6'(7'H)-[4H]naphth[1,8a-b]oxet]-2-one
CAS No.	87587-49-3
Molecular Formula	C23H26O7
Molecular Weight	414.45 g/mol
Synonyms	5-(3-Furanyl)-2'a,3',4,5,5',5'aα,8',9'-octahydro-4'α,9'α-dihydroxy-2'a-(hydroxymethyl)-7'β-methylspiro[furan-3(2H),6'(7'H)-[4H]naphth[1,8a-b]oxet]-2-one; Spiro[naphth[1,8a-b]oxetane-6'(7'H),3'-furan]-2-one derivative; CAS 87587-49-3; (2'aR,3S,5S,9'aR)-rel-5-(3-Furanyl)octahydro-4',9'-dihydroxy-2'-(hydroxymethyl)-7'-methylspiro[furan-3(2H),6'(7'H)-[4H]naphth[1,8a-b]oxet]-2-one
EINECS	Contact for details

Quality Control

Our (2'aR,3S,5S,9'aR)-5-(3-Furanyl)-2'a,3',4,5,5',5'aα,8',9'-octahydro-4'α,9'α-dihydroxy-2'a-(hydroxymethyl)-7'β-methylspiro[furan-3(2H),6'(7'H)-[4H]naphth[1,8a-b]oxet]-2-one is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications and results from techniques such as HPLC, NMR, and chiral analysis are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.