Description

4-[(1E,2E,4R,6E)-8-[(2R,4S,6R,8R,9S)-8-Ethyl-4-hydroxy-9-methyl-1,7-dioxaspiro[5.5]undec-2-yl]-4,6-dimethyl-2,6-octadienylidene]-3,4-dihydro-7-methyl-1H-2-benzopyran-1-one is a complex, high-purity organic compound with a defined stereochemistry, making it a valuable chiral building block and advanced intermediate for sophisticated chemical synthesis. Its intricate spirocyclic and polyene structure is critical for research and development in the pharmaceutical sector, particularly for creating novel therapeutic agents. This compound is essential for R&D chemists and process development teams in fine chemical and pharmaceutical industries seeking to develop new active pharmaceutical ingredients (APIs) and bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel drug candidates, particularly in oncology and anti-infective research.
• Advanced Organic Synthesis: Used as a sophisticated building block for constructing complex natural product analogs and macrocyclic compounds.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new chemical entities for therapeutic applications.
• Process Chemistry Development: Acts as a critical intermediate for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) guidelines.
• Fine Chemical Production: Utilized in the manufacture of high-value specialty chemicals requiring specific stereochemical configurations.
• Reference Standard: Provides a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	4-[(1E,2E,4R,6E)-8-[(2R,4S,6R,8R,9S)-8-Ethyl-4-hydroxy-9-methyl-1,7-dioxaspiro[5.5]undec-2-yl]-4,6-dimethyl-2,6-octadienylidene]-3,4-dihydro-7-methyl-1H-2-benzopyran-1-one
CAS No.	87292-15-7
Molecular Formula	C32H44O4
Molecular Weight	492.70 g/mol
Synonyms	(1E,2E,4R,6E)-8-[(2R,4S,6R,8R,9S)-8-Ethyl-4-hydroxy-9-methyl-1,7-dioxaspiro[5.5]undec-2-yl]-4,6-dimethyl-2,6-octadienylidene]-3,4-dihydro-7-methyl-1H-2-benzopyran-1-one; Spiroketal Benzopyranone Derivative; 87292-15-7; CAS 87292-15-7
EINECS	Contact for details

Quality Control

Our production of 4-[(1E,2E,4R,6E)-8-[(2R,4S,6R,8R,9S)-8-Ethyl-4-hydroxy-9-methyl-1,7-dioxaspiro[5.5]undec-2-yl]-4,6-dimethyl-2,6-octadienylidene]-3,4-dihydro-7-methyl-1H-2-benzopyran-1-one adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and stereochemical integrity. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided, supporting development under quality systems aligned with ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.