Description

2-amino-9-[4-[[5-(2-amino-6-oxo-3H-purin-9-yl)-3-hydroxy-oxolan-2-yl]methoxy-oxido-phosphoryl]oxy-5-(phosphonatomethoxy)oxolan-2-yl]-3H-purin-6-one, azane, hydrogen(+1) cation, platinum(+2) cation is a platinum-based coordination complex of a modified nucleoside analog, representing a sophisticated class of pharmaceutical intermediates. This compound is of significant interest for its potential role in the development of targeted chemotherapeutic agents and advanced nucleotide-based therapeutics. It is primarily utilized by research institutions and pharmaceutical companies engaged in oncology drug discovery, antiviral research, and the synthesis of novel nucleotide prodrugs.

Application

• Pharmaceutical Intermediate: Key precursor in the research and synthesis of platinum-containing anticancer drug candidates and nucleotide analogs.
• Oncology Research: Investigated for its mechanism of action and efficacy in cell-based assays and preclinical studies targeting various cancer cell lines.
• Antiviral Drug Development: Serves as a building block for novel nucleoside phosphonate analogs with potential activity against viral polymerases.
• Biochemical Research: Used as a specialized reagent to study DNA/RNA interaction mechanisms, metal-nucleic acid chemistry, and enzyme inhibition.
• Prodrug Synthesis: Employed in the design and synthesis of nucleotide prodrugs aimed at improving cellular uptake and therapeutic index.

Basic Information

Item	Details
Product Name	2-amino-9-[4-[[5-(2-amino-6-oxo-3H-purin-9-yl)-3-hydroxy-oxolan-2-yl]methoxy-oxido-phosphoryl]oxy-5-(phosphonatomethoxy)oxolan-2-yl]-3H-purin-6-one, azane, hydrogen(+1) cation, platinum(+2) cation
CAS No.	81119-95-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Platinum nucleoside complex; Platinum(II) nucleotide analog; Carboplatin nucleoside derivative; cis-Platinum guanosine analog; Pt-GMP complex; Anticancer platinum nucleotide; Research code 81119-95-1; Platinum-modified antiviral nucleoside
EINECS	Contact for details

Quality Control

Our pharmaceutical-grade intermediates are produced under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure consistency and compliance with research specifications. A detailed Certificate of Analysis (COA) documenting purity, related substances, and residual solvents is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a desiccated environment to prevent degradation. For long-term stability, storage under an inert atmosphere such as argon or nitrogen is recommended.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Heavy Metals (as Pt)	Contact for details
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.