Description

(1aR,7bR)-1aα,2,7aα,13,14,14aα-Hexahydro-1,1,6,6,9,9,11,13α-octamethyl-10aαH-2α,12aα-methano-1H,4H-cyclopropa[5,6][1,3]dioxolo[2',3']cyclopenta[1',2':9,10]cyclodeca[1,2-d][1,3]dioxin-15-ol is a complex, high-purity diterpenoid derivative with a unique polycyclic structure. This compound is valued for its role as a key synthetic intermediate in the development of novel pharmaceutical and agrochemical actives. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, fine chemical, and life science research sectors who require structurally defined, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its complex diterpenoid backbone for bioactivity.
• Fine Chemical Synthesis: Acts as a sophisticated chiral building block for constructing complex natural product analogs and specialty chemicals.
• Academic & Institutional Research: Employed in chemical biology and medicinal chemistry programs to study structure-activity relationships (SAR).
• Process Chemistry Development: Used for scaling up synthetic routes and optimizing yield for advanced intermediates.

Basic Information

Product Name	(1aR,7bR)-1aα,2,7aα,13,14,14aα-Hexahydro-1,1,6,6,9,9,11,13α-octamethyl-10aαH-2α,12aα-methano-1H,4H-cyclopropa[5,6][1,3]dioxolo[2',3']cyclopenta[1',2':9,10]cyclodeca[1,2-d][1,3]dioxin-15-ol
CAS No.	77573-45-6
Molecular Formula	C30H44O5
Molecular Weight	484.67 g/mol
Synonyms	15-Hydroxy-1,1,6,6,9,9,11,13α-octamethyl-1aα,2,7aα,13,14,14aα-hexahydro-10aαH-2α,12aα-methano-1H,4H-cyclopropa[5,6][1,3]dioxolo[2',3']cyclopenta[1',2':9,10]cyclodeca[1,2-d][1,3]dioxin; Polycyclic diterpenoid derivative; CAS 77573-45-6; 15-Hydroxy-octamethyl-hexahydro-methano-cyclopropa-dioxolo-cyclopenta-cyclodeca-dioxin
EINECS	Contact for details

Quality Control

Our (1aR,7bR)-1aα,2,7aα,13,14,14aα-Hexahydro-1,1,6,6,9,9,11,13α-octamethyl-10aαH-2α,12aα-methano-1H,4H-cyclopropa[5,6][1,3]dioxolo[2',3']cyclopenta[1',2':9,10]cyclodeca[1,2-d][1,3]dioxin-15-ol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.