Description

Butyric acid (1aR)-1aα,2β,5,5a,6,9,10,10aα-octahydro-5aβ-hydroxy-4-hydroxymethyl-1,1,7,9α-tetramethyl-6,11-dioxo-1H-2α,8aα-methanocyclopenta[a]cyclopropa[e]cyclodecen-5β-yl ester is a high-purity, complex organic ester derivative of butyric acid, designed for specialized research and development applications. This compound serves as a critical advanced synthetic intermediate for the preparation of novel chemical entities, particularly in the pharmaceutical and agrochemical sectors. Its intricate molecular structure makes it valuable for scientists exploring new synthetic pathways, bioactive molecules, and material science innovations.

Application

• Pharmaceutical Research & Development: As a key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs) and complex natural product analogs.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides, herbicides, and plant growth regulators with specific stereochemical requirements.
• Advanced Material Science: Serves as a precursor for specialty polymers, liquid crystals, or organic electronic materials requiring precise molecular architecture.
• Chemical Biology & Probe Development: Employed in the creation of molecular probes and labeled compounds for studying biological mechanisms and enzyme interactions.
• Process Chemistry & Scale-up: Acts as a critical intermediate in process optimization and pilot-scale synthesis for complex organic molecules.
• Academic & Institutional Research: Utilized in university and institutional labs for fundamental studies in organic synthesis, catalysis, and stereochemistry.

Basic Information

Product Name	Butyric acid (1aR)-1aα,2β,5,5a,6,9,10,10aα-octahydro-5aβ-hydroxy-4-hydroxymethyl-1,1,7,9α-tetramethyl-6,11-dioxo-1H-2α,8aα-methanocyclopenta[a]cyclopropa[e]cyclodecen-5β-yl ester
CAS No.	77508-70-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Butanoic acid, (1aR,2S,5S,5aS,8aS,9R,10aR)-decahydro-5a-hydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-6,11-dioxo-1H-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-5-yl ester; Taxol C-13 side chain butyrate derivative; Paclitaxel side chain ester analog; (1aR,2S,5S,5aS,8aS,9R,10aR)-5a-Hydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-6,11-dioxo-1,1a,2,5,5a,6,9,10,10a,11-decahydro-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-5-yl butyrate
EINECS	Contact for details

Quality Control

Our Butyric acid (1aR)-1aα,2β,5,5a,6,9,10,10aα-octahydro-5aβ-hydroxy-4-hydroxymethyl-1,1,7,9α-tetramethyl-6,11-dioxo-1H-2α,8aα-methanocyclopenta[a]cyclopropa[e]cyclodecen-5β-yl ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term stability, storage at temperatures between 2°C and 8°C (refrigerated) is recommended. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.