Description

(5R,5aα)-5α,8,8aβ,9α-Tetrahydro-9β-[[4-O,6-O-(p-methoxybenzylidene)-β-D-glucopyranosyl]oxy]-5β-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one is a complex, high-purity chemical intermediate characterized by its intricate glycosylated naphthofurodioxole structure. This compound matters as a critical building block in advanced pharmaceutical research, particularly for the synthesis of novel therapeutic agents. It is primarily needed by R&D laboratories and pharmaceutical manufacturers engaged in developing specialized small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex active pharmaceutical ingredients (APIs) for research and development.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Glycosylation Chemistry Studies: Acts as a model compound for investigating glycosylation reactions and protecting group strategies in carbohydrate chemistry.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Biochemical Research: Potential use as a probe or inhibitor in enzymatic studies due to its complex, natural product-like structure.

Basic Information

Product Name	(5R,5aα)-5α,8,8aβ,9α-Tetrahydro-9β-[[4-O,6-O-(p-methoxybenzylidene)-β-D-glucopyranosyl]oxy]-5β-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
CAS No.	73839-76-6
Molecular Formula	C39H38O15
Molecular Weight	746.71 g/mol
Synonyms	9-[(4,6-O-p-Methoxybenzylidene-β-D-glucopyranosyl)oxy]-5-(3,4,5-trimethoxyphenyl)-5,5a,8,8a,9,9a-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one; Podophyllotoxin 4,6-O-p-methoxybenzylidene glucoside derivative; 73839-76-6; Aryl tetralin lignan glucoside; Modified podophyllotoxin glycoside
EINECS	Contact for details

Quality Control

Our (5R,5aα)-5α,8,8aβ,9α-Tetrahydro-9β-[[4-O,6-O-(p-methoxybenzylidene)-β-D-glucopyranosyl]oxy]-5β-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.