Description

(S)-5-[(2'R,2'aS,2R,4S,8'aS)-2'-(3-Furyl)-4,4',5,6'-tetrahydro-5,5-dimethylspiro[furan-2(3H),7'(3'H)-[2H,8aH-2aβ,8bβ]methanofuro[4,3,2-ij][2]benzopyran]-4-yl]-5-methylfuran-2(5H)-one is a high-purity, complex organic compound featuring a unique spirocyclic and fused ring structure. This compound is valued as a critical advanced pharmaceutical intermediate or research chemical for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D organizations and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the research and development of new active pharmaceutical ingredients (APIs), particularly for complex target molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for discovering new drugs, leveraging its intricate molecular architecture.
• Organic Synthesis: Acts as a sophisticated precursor or template for synthesizing novel heterocyclic compounds and natural product analogs in academic and industrial laboratories.
• Chemical Biology Probes: Potential use in the development of specialized probes for studying biological pathways and enzyme interactions due to its specific stereochemistry.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential drug candidates, requiring high chemical purity and batch-to-batch consistency.

Basic Information

Item	Detail
Product Name	(S)-5-[(2'R,2'aS,2R,4S,8'aS)-2'-(3-Furyl)-4,4',5,6'-tetrahydro-5,5-dimethylspiro[furan-2(3H),7'(3'H)-[2H,8aH-2aβ,8bβ]methanofuro[4,3,2-ij][2]benzopyran]-4-yl]-5-methylfuran-2(5H)-one
CAS No.	73744-92-0
Molecular Formula	C27H28O6
Molecular Weight	448.51 g/mol
Synonyms	5-Methyl-5-[(2'R,2'aS,2R,4S,8'aS)-2'-(3-furyl)-4,4',5,6'-tetrahydro-5,5-dimethylspiro[furan-2(3H),7'(3'H)-[2H,8aH-2aβ,8bβ]methanofuro[4,3,2-ij][2]benzopyran]-4-yl]furan-2(5H)-one, (S)-; Spiro[methanofuro[4,3,2-ij][2]benzopyran-furanone] derivative; CAS 73744-92-0; (2S,4S,2'R,2'aS,8'aS)-isomer of the specified furanone. Contact for additional aliases.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality management systems. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), chiral purity, and related substances is provided with every shipment to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.