Description

(3aS,8R,9S,11bR)-3a,4,6a,7,7aα,8,10,11-Octahydro-4α,8-dihydroxy-2',2',5,6aβ,8-pentamethylspiro[5α,11aα-methano-11aH-fluoreno[4,4a-c]furan-9(3H),3'(6'H)-[2H]pyran]-3,6,6'-trione is a complex, high-purity spirocyclic diterpenoid compound with significant biological activity. Its intricate stereochemistry and functional groups make it a valuable intermediate for advanced pharmaceutical research and synthesis. This compound is primarily sought by research institutions and pharmaceutical developers working on novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Biochemical Research: Used as a reference standard or probe in pharmacological studies to investigate specific biological pathways and enzyme interactions.
• Natural Product Synthesis: Acts as a sophisticated intermediate in the total or semi-synthesis of complex natural products with diterpenoid skeletons.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of high-value active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in universities and research institutes for methodological studies in organic synthesis and stereochemistry.

Basic Information

Item	Details
Product Name	(3aS,8R,9S,11bR)-3a,4,6a,7,7aα,8,10,11-Octahydro-4α,8-dihydroxy-2',2',5,6aβ,8-pentamethylspiro[5α,11aα-methano-11aH-fluoreno[4,4a-c]furan-9(3H),3'(6'H)-[2H]pyran]-3,6,6'-trione
CAS No.	72746-68-0
Molecular Formula	C28H34O7
Molecular Weight	482.57 g/mol
Synonyms	Spongian-16-one, 3,19-dideoxy-6,7-didehydro-5,17-dihydroxy-; 3,19-Dideoxy-6,7-didehydro-5,17-dihydroxyspongian-16-one; Spongia diterpenoid derivative; CAS 72746-68-0; Spiro[5α,11aα-methano-11aH-fluoreno[4,4a-c]furan-9(3H),3'(6'H)-[2H]pyran] derivative; Complex spongiane diterpene
EINECS	Contact for details

Quality Control

Our (3aS,8R,9S,11bR)-3a,4,6a,7,7aα,8,10,11-Octahydro-4α,8-dihydroxy-2',2',5,6aβ,8-pentamethylspiro[5α,11aα-methano-11aH-fluoreno[4,4a-c]furan-9(3H),3'(6'H)-[2H]pyran]-3,6,6'-trione is produced under strict quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and stereochemical integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. The container should be kept in a dry, well-ventilated area. For long-term storage, consider inert atmosphere conditions to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.