Description

(E)-2-(Hydroxymethyl)-2-butenoic acid [(E)-2-[[(3aR,4R,6E,10E,11aR)-2,3,3a,4,5,8,9,11a-octahydro-6,10-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-yl]oxycarbonyl]-2-butenyl] ester is a high-purity, complex organic ester with significant potential in advanced chemical synthesis. Its intricate molecular architecture makes it a valuable chiral building block and intermediate for research and development in specialized fields. This compound is primarily targeted at industries focused on pharmaceutical development and fine chemical manufacturing where precise molecular control is paramount.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for complex natural product derivatives.
• Advanced Organic Synthesis: Used as a sophisticated building block for constructing complex macrocyclic or polycyclic molecular frameworks in academic and industrial R&D.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the synthesis of targeted compound libraries for drug discovery programs.
• Fine Chemical Production: Acts as a precursor for the manufacture of high-value specialty chemicals, including flavors, fragrances, and advanced materials.
• Biochemical Research: Potential use as a probe or substrate in enzymatic studies due to its specific stereochemistry and functional groups.

Basic Information

Product Name	(E)-2-(Hydroxymethyl)-2-butenoic acid [(E)-2-[[(3aR,4R,6E,10E,11aR)-2,3,3a,4,5,8,9,11a-octahydro-6,10-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-yl]oxycarbonyl]-2-butenyl] ester
CAS No.	72055-91-5
Molecular Formula	C22H30O6
Molecular Weight	390.47 g/mol
Synonyms	2-Butenoic acid, 2-(hydroxymethyl)-, (E)-, (E)-2-[[(3aR,4R,6E,10E,11aR)-2,3,3a,4,5,8,9,11a-octahydro-6,10-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-yl]oxycarbonyl]-2-butenyl ester; (2E)-2-({[(3aR,4R,6E,10E,11aR)-2,3,3a,4,5,8,9,11a-Octahydro-6,10-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-yl]oxy}carbonyl)-2-buten-1-yl 2-(hydroxymethyl)-2-butenoate; A derivative of Costunolide; Sesquiterpene lactone ester.
EINECS	Contact for details

Quality Control

Our production of (E)-2-(Hydroxymethyl)-2-butenoic acid ester (CAS 72055-91-5) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.