Description

1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-4-{[4-(pent-1-yl)phenyl]sulphonyl}homopiperazine is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound matters as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring high specificity. Research and development teams in the pharmaceutical and agrochemical industries need this precise chemical to develop new drug candidates and crop protection agents targeting specific biological pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drugs, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used in the development of next-generation pesticides and herbicides, leveraging its pyridine and diazepane motifs for biological activity.
• Chemical Biology Probe: Serves as a scaffold for creating tool compounds to study enzyme inhibition and receptor interactions in biochemical assays.
• Organic Synthesis Building Block: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis projects requiring high-fidelity, complex heterocycles.

Basic Information

Product Name	1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-4-{[4-(pent-1-yl)phenyl]sulphonyl}homopiperazine
CAS No.	646456-06-6
Molecular Formula	C23H27ClF3N3O2S
Molecular Weight	501.99 g/mol
Synonyms	3-Chloro-2-(4-{[4-(pent-1-yl)phenyl]sulphonyl}-1,4-diazepan-1-yl)-5-(trifluoromethyl)pyridine; 1,4-Diazepane, 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-4-[[4-(1-pentyl)phenyl]sulfonyl]-; 646456-06-6; 3-Chloro-2-(4-{[4-(pentyl)phenyl]sulfonyl}-1,4-diazepan-1-yl)-5-(trifluoromethyl)pyridine; 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-4-((4-pentylphenyl)sulfonyl)homopiperazine
EINECS	Contact for details

Quality Control

Our production of 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-4-{[4-(pent-1-yl)phenyl]sulphonyl}homopiperazine adheres to stringent quality systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing HPLC purity, NMR confirmation, and residual solvent levels are provided with every shipment to support your regulatory and quality documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible to maximize shelf-life stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.