Description

(3S,4'S,5S)-5-(3-Furyl)-4,5,5',5'aβ,7',8',8'aα,8'b-octahydro-4'β-hydroxy-8'bα-hydroxymethyl-7'-methylenespiro[furan-3(2H),6'-[6H]naphtho[1,8-bc]furan]-2,2'(4'H)-dione is a complex, high-purity spirocyclic furan derivative of significant interest in advanced organic synthesis. This compound serves as a sophisticated chiral building block and key intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought by research institutions and industrial R&D departments focused on medicinal chemistry, asymmetric synthesis, and the exploration of new chemical entities with potential biological activity.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the multi-step synthesis of potential drug candidates, particularly in oncology and anti-infective research.
• Medicinal Chemistry Research: Used as a core scaffold or building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Asymmetric Synthesis: Employed in advanced organic synthesis to introduce complex stereochemistry and furan-based motifs into target molecules.
• Fine Chemical Production: Serves as a specialized intermediate in the manufacture of high-value, low-volume chemicals for agrochemical and material science applications.
• Academic Research: Utilized in universities and research institutes for methodological development in total synthesis and natural product analog creation.

Basic Information

Product Name	(3S,4'S,5S)-5-(3-Furyl)-4,5,5',5'aβ,7',8',8'aα,8'b-octahydro-4'β-hydroxy-8'bα-hydroxymethyl-7'-methylenespiro[furan-3(2H),6'-[6H]naphtho[1,8-bc]furan]-2,2'(4'H)-dione
CAS No.	69749-01-5
Molecular Formula	C23H24O7
Molecular Weight	412.43 g/mol
Synonyms	7'-Methylenespiro[furan-3(2H),6'-[6H]naphtho[1,8-bc]furan]-2,2'(4'H)-dione, 5-(3-furanyl)-4,5,5',5'a,7',8',8'a,8'b-octahydro-4'-hydroxy-8'b-(hydroxymethyl)-, (3S,4'S,5S,5'aβ,8'aα,8'bα)-; Spiro[furan-3(2H),6'-[6H]naphtho[1,8-bc]furan] derivative; CAS 69749-01-5; Advanced spirocyclic furan intermediate; Chiral furan-naphthofuran spiro compound.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and chiral integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality systems are designed to support cGMP compliance for use in pharmaceutical development, ensuring traceability and documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.