Description

(1S,2S,8'R)-7'β-Acetoxy-8'-acetoxymethyl-3',4',4'b,5',6',7',8',8'aβ,9',10'-decahydro-3'β,9'α,10'β-trihydroxy-2,4'bα,8'-trimethylspiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4'-dione is a complex, high-purity steroidal derivative with a unique spirocyclic structure. This compound is of significant interest for its potential as a key synthetic intermediate in advanced pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of novel therapeutic agents, particularly in steroid-based drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new therapeutic candidates.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of complex steroidal molecules.
• Reference Standard: Can be used as an analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Investigated for its interaction with steroid hormone receptors and related biological pathways.

Basic Information

Product Name	(1S,2S,8'R)-7'β-Acetoxy-8'-acetoxymethyl-3',4',4'b,5',6',7',8',8'aβ,9',10'-decahydro-3'β,9'α,10'β-trihydroxy-2,4'bα,8'-trimethylspiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4'-dione
CAS No.	66607-73-6
Molecular Formula	C₂₇H₃₈O₉
Molecular Weight	506.59 g/mol
Synonyms	7'β-Acetoxy-8'-acetoxymethyl-3'β,9'α,10'β-trihydroxy-2,4'bα,8'-trimethylspiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4'-dione; Spirocyclopropanephenanthrenedione derivative; CAS 66607-73-6; 7'-Acetoxy-8'-acetoxymethyl steroidal spirodione; 3'β,9'α,10'β-Trihydroxy-2,4'bα,8'-trimethyl-7'β,8'-diacetoxy-spiro[cyclopropane-1,2'-phenanthrene]-1',4'-dione
EINECS	Contact for details

Quality Control

Our (1S,2S,8'R)-7'β-Acetoxy-8'-acetoxymethyl-3',4',4'b,5',6',7',8',8'aβ,9',10'-decahydro-3'β,9'α,10'β-trihydroxy-2,4'bα,8'-trimethylspiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4'-dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere to prevent oxidation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.