Description

[(2S,2'S)-3β,7β,9α,10β-Tetrakis(acetyloxy)-3,4,4b,5,6,7,8,8a,9,10-decahydro-2',4bα,8-trimethyl-1,4-dioxospiro[phenanthrene-2(1H),1'-cyclopropan]-8β-yl]methanol acetate is a high-purity, complex steroidal derivative of significant interest in advanced pharmaceutical research and development. Its intricate molecular architecture makes it a valuable key intermediate for synthesizing novel therapeutic agents, particularly in the fields of endocrinology and oncology. This compound is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on creating next-generation steroid-based drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of potent steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and the development of new therapeutic candidates targeting hormone receptors.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis using HPLC, LC-MS, or NMR.
• Process Chemistry: Acts as a key intermediate in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Biochemical Research: Utilized in studies investigating steroid metabolism, enzyme inhibition, and molecular signaling pathways.

Basic Information

Product Name	[(2S,2'S)-3β,7β,9α,10β-Tetrakis(acetyloxy)-3,4,4b,5,6,7,8,8a,9,10-decahydro-2',4bα,8-trimethyl-1,4-dioxospiro[phenanthrene-2(1H),1'-cyclopropan]-8β-yl]methanol acetate
CAS No.	66584-90-5
Molecular Formula	C31H40O10
Molecular Weight	572.65 g/mol
Synonyms	8β-Hydroxymethyl-3β,7β,9α,10β-tetraacetoxyspiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4-dione; 8β-(Acetoxymethyl)-3β,7β,9α,10β-tetraacetoxyspiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4-dione; Spirocyclopropane Steroid Derivative; 66584-90-5; (2S,2'S)-3β,7β,9α,10β-Tetraacetoxy-8β-(acetoxymethyl)-2',4bα,8-trimethyl-1,4-dioxospiro[cyclopropane-1,2'(1'H)-phenanthrene]
EINECS	Contact for details

Quality Control

Our [(2S,2'S)-3β,7β,9α,10β-Tetrakis(acetyloxy)-3,4,4b,5,6,7,8,8a,9,10-decahydro-2',4bα,8-trimethyl-1,4-dioxospiro[phenanthrene-2(1H),1'-cyclopropan]-8β-yl]methanol acetate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing results from HPLC, NMR, and other relevant tests are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.