Description

(1S,2S)-10'β-Acetoxy-7'-acetoxymethyl-4'b,5',6',8'aβ,9',10'-hexahydro-3'β,9'α-dihydroxy-2,4'bα,8'-trimethylspiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4'(3'H)-dione is a complex, high-purity steroidal spiro compound with a unique cyclopropane-phenanthrene fused structure. This compound is valued as a critical advanced pharmaceutical intermediate for the research and synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing steroidal drugs and bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel steroidal drugs and hormone analogs.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and drug discovery programs.
• Biochemical Research: Serves as a reference standard or probe in studying steroid receptor interactions and metabolic pathways.
• Fine Chemical Synthesis: Intermediate for the production of complex, high-value specialty chemicals with specific biological activity.
• Academic Research: Utilized in universities and research institutes for synthetic organic chemistry and pharmacology studies.

Basic Information

Item	Details
Product Name	(1S,2S)-10'β-Acetoxy-7'-acetoxymethyl-4'b,5',6',8'aβ,9',10'-hexahydro-3'β,9'α-dihydroxy-2,4'bα,8'-trimethylspiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4'(3'H)-dione
CAS No.	66451-11-4
Molecular Formula	C26H34O8
Molecular Weight	474.55 g/mol
Synonyms	10β-Acetoxy-7-acetoxymethyl-4b,5,6,8aβ,9,10-hexahydro-3β,9α-dihydroxy-2,4bα,8-trimethylspiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4'(3'H)-dione; (1S,2S)-10'-Acetoxy-7'-acetoxymethyl-4'b,5',6',8'aβ,9',10'-hexahydro-3'β,9'-dihydroxy-2,4'bα,8'-trimethylspiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4'(3'H)-dione; Spiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4'(3'H)-dione derivative; Steroidal spiro compound with cyclopropane; CAS 66451-11-4
EINECS	Contact for details

Quality Control

Our (1S,2S)-10'β-Acetoxy-7'-acetoxymethyl-4'b,5',6',8'aβ,9',10'-hexahydro-3'β,9'α-dihydroxy-2,4'bα,8'-trimethylspiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4'(3'H)-dione is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.