Description

2-(Hydroxymethyl)propenoic acid (3aR,9R)-3,3aβ,4,5,6,6aβ,7,8,9aβ,9bα-decahydro-8α-hydroxy-3,6-bis(methylene)-2-oxospiro[azuleno[4,5-b]furan-9(2H),2'-oxirane]-4β-yl ester is a complex, high-purity synthetic intermediate characterized by its intricate spirocyclic and oxirane (epoxide) functional groups. This compound is valued for its role as a versatile building block in advanced organic synthesis, enabling the construction of novel molecular architectures. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, particularly those with complex polycyclic or spirocyclic core structures.
• Medicinal Chemistry Research: Used as a key scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Advanced Organic Synthesis: Employed in academic and industrial R&D for constructing challenging carbon frameworks, leveraging its reactive epoxide and ester functionalities.
• Specialty Fine Chemicals: Acts as a starting material for synthesizing high-value, low-volume chemicals used in material science or as analytical standards.
• Process Chemistry Development: Utilized in route scouting and optimization for the scalable production of complex target molecules.

Basic Information

Product Name	2-(Hydroxymethyl)propenoic acid (3aR,9R)-3,3aβ,4,5,6,6aβ,7,8,9aβ,9bα-decahydro-8α-hydroxy-3,6-bis(methylene)-2-oxospiro[azuleno[4,5-b]furan-9(2H),2'-oxirane]-4β-yl ester
CAS No.	64205-84-1
Molecular Formula	C20H24O6
Molecular Weight	360.40 g/mol
Synonyms	2-(Hydroxymethyl)acrylic Acid (3aR,9R)-3,3aβ,4,5,6,6aβ,7,8,9aβ,9bα-Decahydro-8α-hydroxy-3,6-bis(methylene)-2-oxospiro[azuleno[4,5-b]furan-9(2H),2'-oxirane]-4β-yl Ester; Spiro[azuleno[4,5-b]furan-9(2H),2'-oxirane] Ester Derivative; CAS 64205-84-1; (3aR,9R)-4β-[(2-Hydroxymethyl)propenoyloxy] Decahydro-8α-hydroxy-3,6-bis(methylene)-2-oxospiro[azuleno[4,5-b]furan-9(2H),2'-oxirane]; Azulenofuran Spirooxirane Ester
EINECS	Contact for details

Quality Control

Our 2-(Hydroxymethyl)propenoic acid ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP and ISO 9001 compliant manufacturing upon request, with specifications tailored to meet the rigorous demands of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be sensitive to moisture and should be handled under an inert atmosphere for long-term storage to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.