Description

(1R,2R)-2-[(1aS,8aS)-4β-(3-Furyl)-octahydro-4aβ-methyl-8-methylene-2-oxooxireno[d][2]benzopyran-7α-yl]-2,6,6-trimethyl-5-oxo-3-cyclohexene-1-acetic acid methyl ester is a complex, high-purity synthetic intermediate characterized by its intricate polycyclic structure. This compound is of significant value in advanced organic synthesis, particularly for constructing pharmacologically active scaffolds and natural product analogs. It is primarily sought after by research institutions and pharmaceutical development teams for use in medicinal chemistry, process development, and the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex natural product derivatives and novel drug candidates in medicinal chemistry research.
• Advanced Organic Synthesis: Used in multi-step synthetic routes requiring high stereochemical control and functional group tolerance.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic pathways in pilot plant and manufacturing settings.
• Academic & Industrial Research: Employed in chemical biology studies and the development of new synthetic methodologies.
• Reference Standard: Utilized as a high-purity analytical standard for method development and quality control in related compound synthesis.

Basic Information

Item	Detail
Product Name	(1R,2R)-2-[(1aS,8aS)-4β-(3-Furyl)-octahydro-4aβ-methyl-8-methylene-2-oxooxireno[d][2]benzopyran-7α-yl]-2,6,6-trimethyl-5-oxo-3-cyclohexene-1-acetic acid methyl ester
CAS No.	6488-63-7
Molecular Formula	C28H32O7
Molecular Weight	480.55 g/mol
Synonyms	Methyl (1R,2R)-2-[(1aS,8aS)-4β-(3-Furyl)-octahydro-4aβ-methyl-8-methylene-2-oxooxireno[d][2]benzopyran-7α-yl]-2,6,6-trimethyl-5-oxo-3-cyclohexene-1-acetate; 7α-Methoxycarbonylmethyl-4β-(3-furyl)-1α,2α,6β,7α,8β,8aβ-hexahydro-1β,4aβ,6α-trimethyl-8-methylene-2-oxooxireno[d][2]benzopyran; A related taxane derivative intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is subjected to comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere if opened and resealed for extended periods to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.