Description

(Z)-2-Methyl-2-butenoic acid (3aR,4R,6R,10Z,11aR)-2,3,3a,4,5,6,7,11a-octahydro-10-hydroxymethyl-6-methyl-3-methylene-2,7-dioxo-6,9-epoxycyclodeca[b]furan-4-yl ester is a complex, high-purity organic ester with a defined stereochemistry, making it a valuable chiral building block and intermediate for advanced synthesis. Its intricate molecular architecture is critical for research and development in the life sciences, where precise chemical structure dictates biological activity. This compound is primarily targeted at pharmaceutical R&D and fine chemical synthesis sectors for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for complex natural product derivatives.
• Advanced Organic Synthesis: Used as a specialized building block for constructing complex molecular frameworks in academic and industrial laboratories.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore and optimize biological activity profiles.
• Fine Chemical Production: Acts as a precursor in the multi-step synthesis of high-value specialty chemicals and advanced materials.
• Biochemical Research: Potential use as a probe or inhibitor in enzymatic studies due to its specific stereochemical configuration.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Details
Product Name	(Z)-2-Methyl-2-butenoic acid (3aR,4R,6R,10Z,11aR)-2,3,3a,4,5,6,7,11a-octahydro-10-hydroxymethyl-6-methyl-3-methylene-2,7-dioxo-6,9-epoxycyclodeca[b]furan-4-yl ester
CAS No.	59481-48-0
Molecular Formula	C21H26O8
Molecular Weight	406.43 g/mol
Synonyms	2-Methyl-2-butenoic acid, (3aR,4R,6R,10Z,11aR)-2,3,3a,4,5,6,7,11a-octahydro-10-(hydroxymethyl)-6-methyl-3-methylene-2,7-dioxo-6,9-epoxycyclodeca[b]furan-4-yl ester, (Z)-; Tiglic acid ester derivative of a sesquiterpene lactone; (10Z)-10-(Hydroxymethyl)-6-methyl-3-methylene-2,7-dioxo-6,9-epoxy-2,3,3a,4,5,6,7,11a-octahydrocyclodeca[b]furan-4-yl 2-methylbut-2-enoate; A complex sesquiterpenoid tiglate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Each batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for applications requiring the highest standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The compound may be sensitive to prolonged exposure to moisture and elevated temperatures.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.