Description

2-Methylpropenoic acid (3aR,12R)-3,3aβ,4,5,8,9,9aβ,9bα-octahydro-6α,12-dihydroxy-3-methylene-2-oxo-9α-phenyl-6H-5aβ,9β-propano-2H-furo[2,3-f][2]benzopyran-4β-yl ester is a high-purity, complex organic ester with a defined stereochemistry, making it a valuable intermediate for advanced chemical synthesis. This compound is critical for research and development in the pharmaceutical sector, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and complex natural product analogs. It serves the needs of fine chemical manufacturers, contract research organizations (CROs), and academic institutions focused on medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex, stereospecific drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• Process Chemistry Development: Serves as a critical starting material or intermediate for scaling up synthetic routes under GMP conditions.
• Natural Product Synthesis: Valuable intermediate for the total or semi-synthesis of complex natural products with biological activity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high stereochemical purity.
• Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	2-Methylpropenoic acid (3aR,12R)-3,3aβ,4,5,8,9,9aβ,9bα-octahydro-6α,12-dihydroxy-3-methylene-2-oxo-9α-phenyl-6H-5aβ,9β-propano-2H-furo[2,3-f][2]benzopyran-4β-yl ester
CAS No.	58870-21-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Methacrylic Acid, (3aR,12R)-3,3aβ,4,5,8,9,9aβ,9bα-Octahydro-6α,12-dihydroxy-3-methylene-2-oxo-9α-phenyl-6H-5aβ,9β-propano-2H-furo[2,3-f][2]benzopyran-4β-yl Ester; 2-Propenoic acid, 2-methyl-, (3aR,12R)-3,3aβ,4,5,8,9,9aβ,9bα-octahydro-6α,12-dihydroxy-3-methylene-2-oxo-9α-phenyl-6H-5aβ,9β-propano-2H-furo[2,3-f][2]benzopyran-4β-yl ester; CAS 58870-21-6; 4β-Methacryloyloxy-9α-phenyl-6H-5aβ,9β-propano-2H-furo[2,3-f][2]benzopyran derivative.
EINECS	Contact for details

Quality Control

Our 2-Methylpropenoic acid (3aR,12R)-3,3aβ,4,5,8,9,9aβ,9bα-octahydro-6α,12-dihydroxy-3-methylene-2-oxo-9α-phenyl-6H-5aβ,9β-propano-2H-furo[2,3-f][2]benzopyran-4β-yl ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis and impurity profiling, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.